DeePNAP Input Page

Enter your Protein Sequence, Nucleic Acid Sequence, and any Mutations you wish to analyze.

Make sure that your entries are valid.
The Protein sequence must only have the amino acids ACDEFGHIKLMNPQRSTVWY.
The Nucleic Acid sequence must contain only ATGCU.
The Mutations must follow the correct format.
Hit the find output button. The results will be shown below.

	$ K_D $ Dissociation Rate Constant	$ K_A $ Association Rate Constant	$ \Delta G $ Change in Binding Energy
Wild Type
Mutant Type

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Download Output as CSV

Formulas used to Caluclate the Values

$$K_A = \frac 1 {K_D}$$ $$\Delta G = -RT \ln (K_D)$$ $$ \Delta\Delta G = \Delta G_{mutant} - \Delta G _{wild}$$

	\( K_D \) Dissociation Rate Constant	\( K_A \) Association Rate Constant	\( \Delta G \) Change in Binding Energy
Wild Type
Mutant Type